Current asthma contributes as much as smoking to chronic bronchitis in middle age: A prospective population-based study

SC Dharmage; JL Perret; JA Burgess; CJ Lodge; DP Johns; PS Thomas; GG Giles; JL Hopper; MJ Abramson; E Haydn Walters; MC Matheson

Journal article

Current asthma contributes as much as smoking to chronic bronchitis in middle age: A prospective population-based study

SC Dharmage, JL Perret, JA Burgess, CJ Lodge, DP Johns, PS Thomas, GG Giles, JL Hopper, MJ Abramson, E Haydn Walters, MC Matheson

International Journal of Copd | DOVE MEDICAL PRESS LTD | Published : 2016

DOI: 10.2147/COPD.S103908

Download PDF

Abstract

Background and objective: Personal smoking is widely regarded to be the primary cause of chronic bronchitis (CB) in adults, but with limited knowledge of contributions by other factors, including current asthma. We aimed to estimate the independent and relative contributions to adult CB from other potential influences spanning childhood to middle age. Methods: The population-based Tasmanian Longitudinal Health Study cohort, people born in 1961, completed respiratory questionnaires and spirometry in 1968 (n=8,583). Thirty-seven years later, in 2004, two-thirds responded to a detailed postal survey (n=5,729), from which the presence of CB was established in middle age. A subsample (n=1,389) un..

View full abstract

University of Melbourne Researchers

Shyamali Dharmage Author

Jennifer Perret Author

John Burgess Author

Caroline Lodge Author

Related Projects (2)

Risk factors for chronic respiratory diseases in middle age: 36-year follow up of the Tasmanian Asthma Study

This project will improve our understanding of the causes of chronic respiratory diseases (CRDs) in adults. CRDs are clearly a major public ..

GENETIC AND ENVIRONMENTAL RISK FACTORS ON LIFETIME RISK OF OBSTRUCTIVE LUNG DISEASE

Classification of lifetime phenotypes of obstructive lung disease allows investigation of the effect of environmental and genetic influences..

Grants

Awarded by National Health and Medical Research Council

Funding Acknowledgements

This study was supported by the National Health and Medical Research Council of Australia, research grant 299901; The University of Melbourne; Clifford Craig Medical Research Trust of Tasmania; the Victorian, Queensland & Tasmanian Asthma Foundations; The Royal Hobart Hospital; Helen MacPherson Smith Trust; GlaxoSmithKline; and JLH. SCD, MCM, AJL, EHW, JAB, and JLH are supported by the NHMRC of Australia. JLP is supported by the Center for Air quality and health Research evaluation (CAR), which is also funded by the NHMRC of Australia.